ABSTRACT
Genuine medicinal materials-Fritillariae Cirrhosae Bulbus and its active components are widely used in clinical medicine in China and even in many countries in the world because of their good medicinal effect. However, with the increase of the demand for the resources of Fritillariae Cirrhosae Bulbus, and the low yield of itself, the small number of seeds under natural conditions, the extremely low germination rate and survival rate and so on, the wild resources of Fritillariae Cirrhosae Bulbus are endangered. This paper summarized researches of several aspects like herbal research of Fritillariae Cirrhosae Bulbus, distribution of wild source plant resources and its influencing factors, conservation measures, and using endophyte to extract Fritillaria alkaloids, based on the articles published by China National Knowledge Internet and Web of Science. Hoping to provide some development ideas for the protection of wild source plant resources of Fritillariae Cirrhosae Bulbus from the perspectives of traditional conservation measures and active products extracted by microbial vigorously developed at this stage, so as to realize the balance of supply and demand of Fritillariae Cirrhosae Bulbus as soon as possible.